Orientation of mitotic spindles during the 8- to 16-cell stage transition in mouse embryos.

BACKGROUND:Asymmetric cell divisions are involved in the divergence of the first two lineages of the pre-implantation mouse embryo. They first take place after cell polarization (during compaction) at the 8-cell stage. It is thought that, in contrast to many species, spindle orientation is random, a...

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Bibliographic Details
Main Authors: Nicolas Dard, Sophie Louvet-Vallée, Bernard Maro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2781390?pdf=render