Investigation of characterization and cytotoxic effect of PEGylated nanoliposomal containing Melphalan on ovarian cancer: an in vitro study

Investigation of characterization and cytotoxic effect of PEGylated nanoliposomal containing Melphalan on ovarian cancer: an in vitro study

This study aimed to synthesize Melphalan (MEL)-loaded PEGylated nanoliposomes and evaluate their cytotoxic effects on ovarian cancer A2780CP and SKOV3 cells. For this purpose, MEL-loaded PEGylated nanoliposomes were prepared by the reverse-phase evaporation method. They were then characterized, and...

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Bibliographic Details
Main Authors: Seyedeh Masoomeh Sadat Mirnezami, Amir Heydarinasab, Azim Akbarzadeh, Mehdi Arjmand
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Journal of Experimental Nanoscience
Subjects:
melphalan
pegylated nanoliposome
ovarian cancer
reverse-phase evaporation
mtt
apoptosis
Online Access:http://dx.doi.org/10.1080/17458080.2021.1922669

Internet

http://dx.doi.org/10.1080/17458080.2021.1922669

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