Structure of an odorant-binding protein from the mosquito Aedes aegypti suggests a binding pocket covered by a pH-sensitive "Lid".

BACKGROUND:The yellow fever mosquito, Aedes aegypti, is the primary vector for the viruses that cause yellow fever, mostly in tropical regions of Africa and in parts of South America, and human dengue, which infects 100 million people yearly in the tropics and subtropics. A better understanding of t...

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Bibliographic Details
Main Authors: Ney Ribeiro Leite, Renata Krogh, Wei Xu, Yuko Ishida, Jorge Iulek, Walter S Leal, Glaucius Oliva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2778553?pdf=render