BRAF Testing in Multifocal Papillary Thyroid Carcinoma

Background. BRAF V600E mutation is associated with poor prognosis in patients with papillary thyroid carcinoma (PTC). PTC is often multifocal, and there are no guidelines on how many tumors to test for BRAF mutation in multifocal PTC. Methods. Fifty-seven separate formalin-fixed and paraffin-embedde...

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Bibliographic Details
Main Authors: Hillary Z. Kimbrell, Andrew B. Sholl, Swarnamala Ratnayaka, Shanker Japa, Michelle Lacey, Gandahari Carpio, Parisha Bhatia, Emad Kandil
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/486391