Generation of a CRISPR/Cas9-Based Vector Specific for Gene Manipulation in Leishmania major

Background: Gene manipulation strategies including gene knockout and editing are becoming more sophisticated in terms of mechanism of action, efficacy and ease of use. In classical molecular methods of gene knockout, homologous arms are designed for induction of crossing over event in double strand...

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Bibliographic Details
Main Authors: Ghodratollah SALEHI SANGANI, Vahid JAJARMI, Ali KHAMESIPOUR, Mahmoud MAHMOUDI, Abdolmajid FATA, Mehdi MOHEBALI
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2019-03-01
Series:Iranian Journal of Parasitology
Subjects:
Online Access:http://ijpa.tums.ac.ir/index.php/ijpa/article/view/1782