Matrix Metalloproteinases: The Gene Expression Signatures of Head and Neck Cancer Progression

Extracellular matrix degradation by matrix metalloproteinases (MMPs) plays a pivotal role in cancer progression by promoting motility, invasion and angiogenesis. Studies have shown that MMP expression is increased in head and neck squamous cell carcinomas (HNSCCs), one of the most common cancers in...

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Bibliographic Details
Main Authors: Shinji Iizuka, Naozumi Ishimaru, Yasusei Kudo
Format: Article
Language:English
Published: MDPI AG 2014-02-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/6/1/396