The rapid in vivo evolution of Pseudomonas aeruginosa in ventilator-associated pneumonia patients leads to attenuated virulence
Pseudomonas aeruginosa is an opportunistic pathogen that causes severe airway infections in humans. These infections are usually difficult to treat and associated with high mortality rates. While colonizing the human airways, P. aeruginosa could accumulate genetic mutations that often lead to its be...
Main Authors: | Ke Wang, Yi-qiang Chen, May M. Salido, Gurjeet S. Kohli, Jin-liang Kong, Hong-jie Liang, Zi-ting Yao, Yan-tong Xie, Hua-yu Wu, Shuang-qi Cai, Daniela I. Drautz-Moses, Aaron E. Darling, Stephan C. Schuster, Liang Yang, Yichen Ding |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2017-01-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.170029 |
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