ROLE OF STEM CELL FACTOR IN THE REACTIVATION OF HUMAN FETAL HEMOGLOBIN

In humans the switch from fetal to adult  hemoglobin (HbF→ HbA) takes place in the perinatal and postnatal period, determining the progressive replacement of HbF with HbA synthesis ( i.e., the relative HbF content in red blood cells decreases from 80-90% to <1%). In spite of more than twenty year...

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Bibliographic Details
Main Authors: Marco Gabbianelli, Ugo Testa
Format: Article
Language:English
Published: PAGEPress Publications 2009-11-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Online Access:http://www.mjhid.org/index.php/mjhid/article/view/127