Oligodendrocyte myelin glycoprotein as a novel target for pathogenic autoimmunity in the CNS

Abstract Autoimmune disorders of the central nervous system (CNS) comprise a broad spectrum of clinical entities. The stratification of patients based on the recognized autoantigen is of great importance for therapy optimization and for concepts of pathogenicity, but for most of these patients, the...

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Main Authors: Ramona Gerhards, Lena Kristina Pfeffer, Jessica Lorenz, Laura Starost, Luise Nowack, Franziska S. Thaler, Miriam Schlüter, Heike Rübsamen, Caterina Macrini, Stephan Winklmeier, Simone Mader, Mattias Bronge, Hans Grönlund, Regina Feederle, Hung-En Hsia, Stefan F. Lichtenthaler, Juliane Merl-Pham, Stefanie M. Hauck, Tanja Kuhlmann, Isabel J. Bauer, Eduardo Beltran, Lisa Ann Gerdes, Aleksandra Mezydlo, Amit Bar-Or, Brenda Banwell, Mohsen Khademi, Tomas Olsson, Reinhard Hohlfeld, Hans Lassmann, Tania Kümpfel, Naoto Kawakami, Edgar Meinl
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Acta Neuropathologica Communications
Subjects:
Online Access:https://doi.org/10.1186/s40478-020-01086-2