Human Paramyxovirus Infections Induce T Cells That Cross-React with Zoonotic Henipaviruses

Human Paramyxovirus Infections Induce T Cells That Cross-React with Zoonotic Henipaviruses

Humans encounter multiple paramyxoviruses early in life. This study shows that infection with common paramyxoviruses can induce T cells cross-reactive with the highly pathogenic Nipah virus. This demonstrates that the combination of paramyxovirus infection history and HLA haplotype affects immunity...

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Bibliographic Details
Main Authors: Rory D. de Vries, Alwin de Jong, R. Joyce Verburgh, Lucie Sauerhering, Gijsbert P. van Nierop, Robert S. van Binnendijk, Albert D. M. E. Osterhaus, Andrea Maisner, Marion P. G. Koopmans, Rik L. de Swart
Format: Article
Language:English
Published: American Society for Microbiology 2020-07-01
Series:mBio
Subjects:
paramyxovirus
t cells
measles virus
nipah virus
human parainfluenza virus
Online Access:https://doi.org/10.1128/mBio.00972-20

Internet

https://doi.org/10.1128/mBio.00972-20

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