Epigenetic activation and silencing of the gene that encodes IFN-γ

Epigenetic activation and silencing of the gene that encodes IFN-γ

Transcriptional activation and repression of genes that are developmentally regulated or exhibit cell-type specific expression patterns is largely achieved by modifying the chromatin template at a gene locus. Complex formation of stable epigenetic histone marks, loss or gain of DNA methylation, alte...

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Bibliographic Details
Main Authors: Thomas Martin Aune, Patrick L Collins, Sarah P Collier, Melodie A Henderson, Shaojing eChang
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Immunology
Subjects:
Interferon-gamma
epigenetics
long non-coding RNA
Natural Killer cells
T helper cells
natural killer T cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00112/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00112/full

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