Evolutionary genomics and adaptive evolution of the Hedgehog gene family (Shh, Ihh and Dhh) in vertebrates.

The Hedgehog (Hh) gene family codes for a class of secreted proteins composed of two active domains that act as signalling molecules during embryo development, namely for the development of the nervous and skeletal systems and the formation of the testis cord. While only one Hh gene is found typical...

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Bibliographic Details
Main Authors: Joana Pereira, Warren E Johnson, Stephen J O'Brien, Erich D Jarvis, Guojie Zhang, M Thomas P Gilbert, Vitor Vasconcelos, Agostinho Antunes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0074132