A homeostatic model of neuronal firing governed by feedback signals from the extracellular matrix.

Molecules of the extracellular matrix (ECM) can modulate the efficacy of synaptic transmission and neuronal excitability. These mechanisms are crucial for the homeostatic regulation of neuronal firing over extended timescales. In this study, we introduce a simple mathematical model of neuronal spiki...

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Bibliographic Details
Main Authors: Victor Kazantsev, Susan Gordleeva, Sergey Stasenko, Alexander Dityatev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3407243?pdf=render