System for quantitative evaluation of DAB&H-stained breast cancer biopsy digital images (CHISEL)

Abstract This study presents CHISEL (Computer-assisted Histopathological Image Segmentation and EvaLuation), an end-to-end system capable of quantitative evaluation of benign and malignant (breast cancer) digitized tissue samples with immunohistochemical nuclear staining of various intensity and div...

Full description

Bibliographic Details
Main Authors: Lukasz Roszkowiak, Anna Korzynska, Krzysztof Siemion, Jakub Zak, Dorota Pijanowska, Ramon Bosch, Marylene Lejeune, Carlos Lopez
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88611-y