H4K20me3 co-localizes with activating histone modifications at transcriptionally dynamic regions in embryonic stem cells

Abstract Background Bivalent chromatin domains consisting of the activating histone 3 lysine 4 trimethylation (H3K4me3) and repressive histone 3 lysine 27 trimethylation (H3K27me3) histone modifications are enriched at developmental genes that are repressed in embryonic stem cells but active during...

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Bibliographic Details
Main Authors: Jian Xu, Benjamin L. Kidder
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-018-4886-4