The shared genetic architecture between epidemiological and behavioral traits with lung cancer

Abstract The complex polygenic nature of lung cancer is not fully characterized. Our study seeks to identify novel phenotypes associated with lung cancer using cross-trait linkage disequilibrium score regression (LDSR). We measured pairwise genetic correlation (rg) and SNP heritability (h2) between...

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Bibliographic Details
Main Authors: Rowland W. Pettit, Jinyoung Byun, Younghun Han, Quinn T. Ostrom, Jacob Edelson, Kyle M. Walsh, Melissa L. Bondy, Rayjean J. Hung, James D. McKay, Christopher I. Amos
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96685-x