Rapid genetic algorithm optimization of a mouse computational model: Benefits for anthropomorphization of neonatal mouse cardiomyocytes

While the mouse presents an invaluable experimental model organism in biology, its usefulness in cardiac arrhythmia research is limited in some aspects due to major electrophysiological differences between murine and human action potentials (APs). As previously described, these species-specific trai...

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Bibliographic Details
Main Authors: Corina Teodora Bot, Armen R. Kherlopian, Francis A. Ortega, David J. Christini, Trine eKrogh-Madsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00421/full