Perinatal hormones favor CC17 group B Streptococcus intestinal translocation through M cells and hypervirulence in neonates

Perinatal hormones favor CC17 group B Streptococcus intestinal translocation through M cells and hypervirulence in neonates

Group B Streptococcus (GBS) is the leading cause of invasive bacterial neonatal infections. Late-onset diseases (LOD) occur between 7 and 89 days of life and are largely due to the CC17 GBS hypervirulent clone. We studied the impact of estradiol (E2) and progesterone (P4), which impregnate the fetus...

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Bibliographic Details
Main Authors: Constantin Hays, Gérald Touak, Abdelouhab Bouaboud, Agnès Fouet, Julie Guignot, Claire Poyart, Asmaa Tazi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-11-01
Series:eLife
Subjects:
Streptococcus agalactiae
CC17 clone
intestinal barrier
neonatal infection
sex hormones
M cells
Online Access:https://elifesciences.org/articles/48772

Internet

https://elifesciences.org/articles/48772

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