Exosomes From M2 Macrophage Promote Peritendinous Fibrosis Posterior Tendon Injury via the MiR-15b-5p/FGF-1/7/9 Pathway by Delivery of circRNA-Ep400

Exosomes From M2 Macrophage Promote Peritendinous Fibrosis Posterior Tendon Injury via the MiR-15b-5p/FGF-1/7/9 Pathway by Delivery of circRNA-Ep400

Achilles tendon rupture prognosis is usually unsatisfactory. After the tendon is injured, it may not function properly because of the fibrotic healing response, which restrains tendon motion. Inflammatory monocytes and tissue-resident macrophages are indispensable regulators in tissue repair, fibros...

Full description

Bibliographic Details
Main Authors: Yinxian Yu, Binbin Sun, Zhuoying Wang, Mengkai Yang, Zhi Cui, Subin Lin, Mingming Jin, Chengqing Yi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
M2 macrophage
exosomes
circRNA-Ep400
tendon injury
miR-15b-5p
FGF-1/7/9
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.595911/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.595911/full

Similar Items