Serum and Fecal Markers of Intestinal Inflammation and Intestinal Barrier Permeability Are Elevated in Parkinson’s Disease

Serum and Fecal Markers of Intestinal Inflammation and Intestinal Barrier Permeability Are Elevated in Parkinson’s Disease

Parkinson’s disease (PD) is characterized by alpha-synuclein misfolding with subsequent intraneuronal amyloid formation and accumulation, low grade neuroinflammatory changes, and selective neurodegeneration. Available evidence suggests that the pathology usually begins in the gut and olfactory mucos...

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Bibliographic Details
Main Authors: Laura Dumitrescu, Daciana Marta, Adela Dănău, Antonia Lefter, Delia Tulbă, Liviu Cozma, Emilia Manole, Mihaela Gherghiceanu, Laura Cristina Ceafalan, Bogdan Ovidiu Popescu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Neuroscience
Subjects:
calprotectin
Parkinson’s disease
intestinal inflammation
intestinal barrier permeability
zonulin
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.689723/full

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https://www.frontiersin.org/articles/10.3389/fnins.2021.689723/full

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