Functional Coupling between the P2X<sub>7</sub> Receptor and Pannexin-1 Channel in Rat Trigeminal Ganglion Neurons

Functional Coupling between the P2X<sub>7</sub> Receptor and Pannexin-1 Channel in Rat Trigeminal Ganglion Neurons

The ionotropic P2X receptor, P2X<sub>7</sub>, is believed to regulate and/or generate nociceptive pain, and pain in several neuropathological diseases. Although there is a known relationship between P2X<sub>7</sub> receptor activity and pain sensing, its detailed functional p...

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Bibliographic Details
Main Authors: Hiroyuki Inoue, Hidetaka Kuroda, Wataru Ofusa, Sadao Oyama, Maki Kimura, Tatsuya Ichinohe, Yoshiyuki Shibukawa
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
P2X receptor
pannexin-1 channel
trigeminal ganglion neuron
patch-clamp technique
pain
tooth pain
Online Access:https://www.mdpi.com/1422-0067/22/11/5978

Internet

https://www.mdpi.com/1422-0067/22/11/5978

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