Modeling Native EHEC Outer Membrane Vesicles by Creating Synthetic Surrogates

Enterohemorrhagic <i>Escherichia coli</i> (EHEC) is a zoonotic pathogen responsible for life-threating diseases such as hemolytic uremic syndrome. While its major virulence factor, the Shiga toxin (Stx), is known to exert its cytotoxic effect on various endothelial and epithelial cells w...

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Bibliographic Details
Main Authors: Alexander Kehl, Ronja Kuhn, Johanna Detzner, Daniel Steil, Johannes Müthing, Helge Karch, Alexander Mellmann
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Microorganisms
Subjects:
OMV
Stx
Online Access:https://www.mdpi.com/2076-2607/8/5/673