A new branched proximity hybridization assay for the quantification of nanoscale protein-protein proximity.

Membrane proteins are organized in nanoscale compartments. Their reorganization plays a crucial role in receptor activation and cell signaling. To monitor the organization and reorganization of membrane proteins, we developed a new branched proximity hybridization assay (bPHA) allowing better quanti...

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Bibliographic Details
Main Authors: Shuangshuang Zheng, Melanie Sieder, Michael Mitterer, Michael Reth, Marco Cavallari, Jianying Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000569