Quantitative analysis reveals crosstalk mechanisms of heat shock-induced attenuation of NF-κB signaling at the single cell level.

Quantitative analysis reveals crosstalk mechanisms of heat shock-induced attenuation of NF-κB signaling at the single cell level.

Elevated temperature induces the heat shock (HS) response, which modulates cell proliferation, apoptosis, the immune and inflammatory responses. However, specific mechanisms linking the HS response pathways to major cellular signaling systems are not fully understood. Here we used integrated computa...

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Bibliographic Details
Main Authors: Małgorzata Kardyńska, Anna Paszek, Jarosław Śmieja, David Spiller, Wiesława Widłak, Michael R H White, Pawel Paszek, Marek Kimmel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5945226?pdf=render

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http://europepmc.org/articles/PMC5945226?pdf=render

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