Active Degradation Explains the Distribution of Nuclear Proteins during Cellular Senescence.

The amount of cellular proteins is a crucial parameter that is known to vary between cells as a function of the replicative passages, and can be important during physiological aging. The process of protein degradation is known to be performed by a series of enzymatic reactions, ranging from an initi...

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Bibliographic Details
Main Authors: Enrico Giampieri, Marco De Cecco, Daniel Remondini, John Sedivy, Gastone Castellani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4483236?pdf=render