Renin-Angiotensin System Responds to Prolonged Hypotensive Effect Induced by Mandibular Extension in Spontaneously Hypertensive Rats

There is an ongoing interest in the renin-angiotensin system (RAS) contribution either to pathological mechanisms leading to hypertension (mainly regarding the ACE/AngII/AT1R axis), or, to RAS protective and pro-regenerative actions, primarily ascribed to the mediation of the AT2R and the MAS1 recep...

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Bibliographic Details
Main Authors: Laura Sabatino, Chiara Costagli, Dominga Lapi, Cristina Del Seppia, Giuseppe Federighi, Silvana Balzan, Antonio Colantuoni, Giorgio Iervasi, Rossana Scuri
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01613/full