Interaction between Antifungal Isoxazolo[3,4-<i>b</i>]Pyridin 3(1<i>H</i>)-One Derivatives and Human Serum Proteins Analyzed with Biomimetic Chromatography and QSAR Approach

Interaction between Antifungal Isoxazolo[3,4-<i>b</i>]Pyridin 3(1<i>H</i>)-One Derivatives and Human Serum Proteins Analyzed with Biomimetic Chromatography and QSAR Approach

The development of effective, nontoxic antifungal agents is one of the most important challenges for medicinal chemistry. A series of isoxazolo [3,4-<i>b</i>]pyridine-3(1<i>H</i>)-one derivatives previously synthesized in our laboratory demonstrated promising antifungal prope...

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Bibliographic Details
Main Authors: Krzesimir Ciura, Joanna Fedorowicz, Hanna Kapica, Monika Pastewska, Wiesław Sawicki, Jarosław Sączewski
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Processes
Subjects:
human serum albumin (HSA)
biomimetic chromatography
isoxazolone
QSRR analysis
Online Access:https://www.mdpi.com/2227-9717/9/3/512

Internet

https://www.mdpi.com/2227-9717/9/3/512

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