Early 18F-FDG PET/CT Evaluation Shows Heterogeneous Metabolic Responses to Anti-EGFR Therapy in Patients with Metastatic Colorectal Cancer.

OBJECTIVE:The aim of this pilot study was to explore intrapatient mixed metabolic response and early 18F-FDG PET response evaluation using predefined quantification strategies in patients with advanced KRAS wild-type colorectal adenocarcinoma (mCRC) treated with cetuximab. METHODS:A 18F-FDG PET was...

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Bibliographic Details
Main Authors: Erik J van Helden, Otto S Hoekstra, Ronald Boellaard, Chantal Roth, Emma R Mulder, Henk M W Verheul, C Willemien Menke-van der Houven van Oordt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4873260?pdf=render