Evaluation of D-loop hypervariable region I variations, haplogroups and copy number of mitochondrial DNA in Bangladeshi population with type 2 diabetes

Evaluation of D-loop hypervariable region I variations, haplogroups and copy number of mitochondrial DNA in Bangladeshi population with type 2 diabetes

The profound impact of mitochondrion in cellular metabolism has been well documented. Since type 2 diabetes (T2D) is a metabolic disorder, mitochondrial dysfunction is intricately linked with the disease pathogenesis. Mitochondrial DNA (mtDNA) variants are involved with functional dysfunction of mit...

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Bibliographic Details
Main Authors: Sajoy Kanti Saha, Abdullah Al Saba, Md. Hasib, Razoan Al Rimon, Imrul Hasan, Md. Sohrab Alam, Ishtiaq Mahmud, A.H.M. Nurun Nabi
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Heliyon
Subjects:
Mitochondria
Mitochondrial DNA
D-loop
Hypervariable region
Haplogroup
Type 2 diabetes
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021016765

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http://www.sciencedirect.com/science/article/pii/S2405844021016765

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