Loss of Axon Bifurcation in Mesencephalic Trigeminal Neurons Impairs the Maximal Biting Force in Npr2-Deficient Mice

Loss of Axon Bifurcation in Mesencephalic Trigeminal Neurons Impairs the Maximal Biting Force in Npr2-Deficient Mice

Bifurcation of axons from dorsal root ganglion (DRG) and cranial sensory ganglion (CSG) neurons is mediated by a cGMP-dependent signaling pathway composed of the ligand C-type natriuretic peptide (CNP), the receptor guanylyl cyclase Npr2 and the cGMP-dependent protein kinase I (cGKI). Here, we demon...

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Bibliographic Details
Main Authors: Gohar Ter-Avetisyan, Alexandre Dumoulin, Anthony Herrel, Hannes Schmidt, Johanna Strump, Shoaib Afzal, Fritz G. Rathjen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
axonal branching
mesencephalic trigeminal neurons
cGMP signaling
Npr2
CNP
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00153/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00153/full

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