Gene duplication and phenotypic changes in the evolution of mammalian metabolic networks.

Metabolic networks attempt to describe the complete suite of biochemical reactions available to an organism. One notable feature of these networks in mammals is the large number of distinct proteins that catalyze the same reaction. While the existence of these isoenzymes has long been known, their e...

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Bibliographic Details
Main Authors: Michaël Bekaert, Gavin C Conant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24489850/pdf/?tool=EBI