The DNMT1-associated lincRNA DACOR1 reprograms genome-wide DNA methylation in colon cancer

The DNMT1-associated lincRNA DACOR1 reprograms genome-wide DNA methylation in colon cancer

Abstract Background DNA methylation is a key epigenetic mark in mammalian organisms that plays key roles in chromatin organization and gene expression. Although DNA methylation in gene promoters is generally associated with gene repression, recent studies demonstrate that DNA methylation in gene bod...

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Bibliographic Details
Main Authors: Saigopal Somasundaram, Megan E Forrest, Helen Moinova, Allison Cohen, Vinay Varadan, Thomas LaFramboise, Sanford Markowitz, Ahmad M Khalil
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Clinical Epigenetics
Subjects:
Colon cancer
Epigenetics
lincRNAs
Tumorigenesis
Online Access:http://link.springer.com/article/10.1186/s13148-018-0555-3

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http://link.springer.com/article/10.1186/s13148-018-0555-3

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