Phytoestrogen coumestrol improves mitochondrial activity and decreases oxidative stress in the brain of ovariectomized Wistar-Han rats

After the cessation of estradiol (E2) production by the ovaries, mitochondrial function is affected in several organs, as demonstrated in animal models of menopause. Coumestrol is a phytocompound belonging to the coumestan family, showing higher binding affinity for estrogen receptors beta (ERβ) and...

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Bibliographic Details
Main Authors: Ana C. Moreira, Ana M. Silva, Ana F. Branco, Inês Baldeiras, Gonçalo C. Pereira, Raquel Seiça, Maria S. Santos, Vilma A. Sardão
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617302505