Instant activation of TRP channels by NH4+ promotes neuronal bursting and glutamate spikes in CA1 neurons
Ammonia (NH4+) is a by-product of cell metabolism and may elicit subcellular effects with specific physiological responses. Chronic effects have been implicated in several neurological diseases and attributed to persistent elevation in blood ammonia levels transferred to the brain. In previous studi...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-12-01
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Series: | Current Research in Physiology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2665944120300079 |