Comparing platforms for C. elegans mutant identification using high-throughput whole-genome sequencing.

Whole-genome sequencing represents a promising approach to pinpoint chemically induced mutations in genetic model organisms, thereby short-cutting time-consuming genetic mapping efforts.We compare here the ability of two leading high-throughput platforms for paired-end deep sequencing, SOLiD (ABI) a...

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Bibliographic Details
Main Authors: Yufeng Shen, Sumeet Sarin, Ye Liu, Oliver Hobert, Itsik Pe'er
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2603312?pdf=render