Characterization of the endothelial cell cytoskeleton following HLA class I ligation.

Vascular endothelial cells (ECs) are a target of antibody-mediated allograft rejection. In vitro, when the HLA class I molecules on the surface of ECs are ligated by anti-HLA class I antibodies, cell proliferation and survival pathways are activated and this is thought to contribute to the developme...

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Bibliographic Details
Main Authors: Mary E Ziegler, Puneet Souda, Yi-Ping Jin, Julian P Whitelegge, Elaine F Reed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3256144?pdf=render