Rational Design of Constrained Peptides as Protein Interface Inhibitors

The lack of progress in developing targeted therapeutics directed at protein–protein complexes has been due to the absence of well-defined ligand-binding pockets and the extensive intermolecular contacts at the protein–protein interface. Our laboratory has developed approaches to dissect protein–pro...

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Bibliographic Details
Main Authors: Ramachandran Murali, Hongtao Zhang, Zheng Cai, Lian Lam, Mark Greene
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Antibodies
Subjects:
TNF
Online Access:https://www.mdpi.com/2073-4468/10/3/32