Genistein Improves Skin Flap Viability in Rats: A Preliminary In Vivo and In Vitro Investigation

Genistein Improves Skin Flap Viability in Rats: A Preliminary In Vivo and In Vitro Investigation

Selective estrogen receptor modulators (SERMs) have been developed to achieve beneficial effects of estrogens while minimizing their side effects. In this context, we decided to evaluate the protective effect of genistein, a natural SERM, on skin flap viability in rats and in a series of in vitro ex...

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Bibliographic Details
Main Authors: Lenka Fáber, Ivan Kováč, Petra Mitrengová, Martin Novotný, Lenka Varinská, Tomáš Vasilenko, Martin Kello, Matúš Čoma, Tomáš Kuruc, Klaudia Petrová, Ivana Miláčková, Anika Kuczmannová, Vlasta Peržeľová, Štefánia Mižáková, Erik Dosedla, František Sabol, Ján Luczy, Milan Nagy, Jaroslav Majerník, Martin Koščo, Pavel Mučaji, Peter Gál
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Molecules
Subjects:
wound healing
skin repair
ischemia
estrogen
flap surgery
endothelial cell
SOD
CAT
Bcl-2
Online Access:http://www.mdpi.com/1420-3049/23/7/1637

Internet

http://www.mdpi.com/1420-3049/23/7/1637

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