Controlled Release of Nor-β-lapachone by PLGA Microparticles: A Strategy for Improving Cytotoxicity against Prostate Cancer Cells

Controlled Release of Nor-β-lapachone by PLGA Microparticles: A Strategy for Improving Cytotoxicity against Prostate Cancer Cells

Prostate cancer is one of the most common malignant tumors in males and it has become a major worldwide public health problem. This study characterizes the encapsulation of Nor-β-lapachone (NβL) in poly(d,l-lactide-co-glycolide) (PLGA) microcapsules and evaluates the cytotoxicity of the resulting dr...

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Bibliographic Details
Main Authors: Marcilia P. Costa, Anderson C. S. Feitosa, Fátima C. E. Oliveira, Bruno C. Cavalcanti, Eufrânio N. da Silva, Gleiston G. Dias, Francisco A. M. Sales, Bruno L. Sousa, Ito L. Barroso-Neto, Cláudia Pessoa, Ewerton W. S. Caetano, Stefano Di Fiore, Rainer Fischer, Luiz O. Ladeira, Valder N. Freire
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Molecules
Subjects:
nor-β-lapachone
lapachol
naphthoquinone
cancer
PLGA microcapsules
prostate
Online Access:http://www.mdpi.com/1420-3049/21/7/873

Internet

http://www.mdpi.com/1420-3049/21/7/873

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