Enhancing plasticity in central networks improves motor and sensory recovery after nerve damage

Peripheral nerve damage generates maladaptive neuroplasticity as central networks attempt to compensate for the loss of peripheral connectivity. Here, the authors reverse the aberrant plasticity via vagus nerve stimulation to elicit synaptic reorganization and to improve sensorimotor recovery.

Bibliographic Details
Main Authors: Eric C. Meyers, Nimit Kasliwal, Bleyda R. Solorzano, Elaine Lai, Geetanjali Bendale, Abigail Berry, Patrick D. Ganzer, Mario Romero-Ortega, Robert L. Rennaker, Michael P. Kilgard, Seth A. Hays
Format: Article
Language:English
Published: Nature Publishing Group 2019-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13695-0