Melanoma and the Unfolded Protein Response
The UPR (unfolded protein response) has been identified as a key factor in the progression and metastasis of cancers, notably melanoma. Several mediators of the UPR are upregulated in cancers, e.g., high levels of GRP78 (glucose-regulator protein 78 kDa) correlate with progression and poor outcome i...
Main Authors: | Erin K. Sykes, Swetlana Mactier, Richard I. Christopherson |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-02-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/8/3/30 |
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