Store-independent modulation of Ca2+ entry through Orai by Septin 7

Orai channels are well known to mediate store-operated calcium entry. Here authors show that in neurons of the Drosophilaflight circuit, Septin 7 acts as a negative regulator of Orai channels, surprisingly, by modulating store-independent calcium entry through Orai.

Bibliographic Details
Main Authors: Bipan Kumar Deb, Trayambak Pathak, Gaiti Hasan
Format: Article
Language:English
Published: Nature Publishing Group 2016-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11751