Targeting Nuclear Exporter Protein XPO1/CRM1 in Gastric Cancer

Targeting Nuclear Exporter Protein XPO1/CRM1 in Gastric Cancer

Gastric cancer remains an unmet clinical problem in urgent need of newer and effective treatments. Here we show that the nuclear export protein, Exportin 1 (XPO1, chromosome region maintenance 1 or CRM1), is a promising molecular target in gastric cancer. We demonstrate significant overexpression of...

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Bibliographic Details
Main Authors: Rachel Sexton, Zaid Mahdi, Rahman Chaudhury, Rafic Beydoun, Amro Aboukameel, Husain Y. Khan, Erkan Baloglu, William Senapedis, Yosef Landesman, Anteneh Tesfaye, Steve Kim, Philip A. Philip, Asfar S. Azmi
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
gastric cancer
nuclear protein transport
xpo1/crm1
sine
mirna
Online Access:https://www.mdpi.com/1422-0067/20/19/4826

Internet

https://www.mdpi.com/1422-0067/20/19/4826

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