Maintaining immunogenicity of blood stage and sexual stage subunit malaria vaccines when formulated in combination.

BACKGROUND:Eradication of Plasmodium falciparum malaria will likely require a multivalent vaccine, but the development of a highly efficacious subunit-based formulation has been challenging. We previously showed that production and immunogenicity of two leading vaccine targets, PfMSP119 (blood-stage...

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Bibliographic Details
Main Authors: Elizabeth M Parzych, Kazutoyo Miura, Carole A Long, James M Burns
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232355