Changing the Face of Kynurenines and Neurotoxicity: Therapeutic Considerations

Kynurenines are the products of tryptophan metabolism. Among them, kynurenine and kynurenic acid are generally thought to have neuroprotective properties, while 3-hydroxykynurenine, 3-hydroxyanthranilic acid and quinolinic acid are considered neurotoxic. They participate in immunoregulation and infl...

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Bibliographic Details
Main Authors: Zsuzsanna Bohár, József Toldi, Ferenc Fülöp, László Vécsei
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/16/5/9772