Impaired glucose tolerance in a mouse model of sidt2 deficiency.

Sidt2 was identified as a novel integral lysosomal membrane protein recently. We generated global Sidt2 knockout mice by gene targeting. These mice have a comparatively higher random and fasting glucose concentration. Intraperitoneal and oral glucose tolerance tests in Sidt2 knockout mice indicated...

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Bibliographic Details
Main Authors: Jialin Gao, Xuefan Gu, Don J Mahuran, Zhugang Wang, Huiwen Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3679015?pdf=render