Nicotine Causes Nephrotoxicity through the Induction of NLRP6 Inflammasome and Alpha7 Nicotinic Acetylcholine Receptor

Current cigarette smoking is associated with chronic kidney disease (CKD) or death from end-stage renal disease (ESRD). Mainstream cigarette smoke includes over 4000 compounds. Among the compounds present in tobacco smoke, nicotine is one of a large number of biologically stable and active compounds...

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Bibliographic Details
Main Authors: Cai-Mei Zheng, Yu-Hsuan Lee, I-Jen Chiu, Yu-Jhe Chiu, Li-Chin Sung, Yung-Ho Hsu, Hui-Wen Chiu
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Toxics
Subjects:
Online Access:https://www.mdpi.com/2305-6304/8/4/92