Efficacy of oral immunotherapy with a rice-based edible vaccine containing hypoallergenic Japanese cedar pollen allergens for treatment of established allergic conjunctivitis in mice

Efficacy of oral immunotherapy with a rice-based edible vaccine containing hypoallergenic Japanese cedar pollen allergens for treatment of established allergic conjunctivitis in mice

Background: We have previously shown that prophylactic oral administration of transgenic rice seeds expressing hypoallergenic modified antigens suppressed the development of allergic conjunctivitis induced by Japanese cedar pollen. We have now investigated the efficacy of oral immunotherapy with suc...

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Bibliographic Details
Main Authors: Ken Fukuda, Waka Ishida, Yosuke Harada, Yuhya Wakasa, Hidenori Takagi, Fumio Takaiwa, Atsuki Fukushima
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Allergology International
Subjects:
Allergic conjunctivitis
Immunotherapy
Oral tolerance
Pollen
Transgenic rice
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893017300709

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http://www.sciencedirect.com/science/article/pii/S1323893017300709

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