Differential Connexin Function Enhances Self-Renewal in Glioblastoma

The coordination of complex tumor processes requires cells to rapidly modify their phenotype and is achieved by direct cell-cell communication through gap junction channels composed of connexins. Previous reports have suggested that gap junctions are tumor suppressive based on connexin 43 (Cx43), bu...

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Bibliographic Details
Main Authors: Masahiro Hitomi, Loic P. Deleyrolle, Erin E. Mulkearns-Hubert, Awad Jarrar, Meizhang Li, Maksim Sinyuk, Balint Otvos, Sylvain Brunet, William A. Flavahan, Christopher G. Hubert, Winston Goan, James S. Hale, Alvaro G. Alvarado, Ao Zhang, Mark Rohaus, Muna Oli, Vinata Vedam-Mai, Jeff M. Fortin, Hunter S. Futch, Benjamin Griffith, Qiulian Wu, Chun-hong Xia, Xiaohua Gong, Manmeet S. Ahluwalia, Jeremy N. Rich, Brent A. Reynolds, Justin D. Lathia
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715004088