Identification of proteins sensitive to thermal stress in human neuroblastoma and glioma cell lines.

Heat-shock is an acute insult to the mammalian proteome. The sudden elevation in temperature has far-reaching effects on protein metabolism, leads to a rapid inhibition of most protein synthesis, and the induction of protein chaperones. Using heat-shock in cells of neuronal (SH-SY5Y) and glial (CCF-...

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Bibliographic Details
Main Authors: Guilian Xu, Stanley M Stevens, Firas Kobeissy, Hilda Brown, Scott McClung, Mark S Gold, David R Borchelt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3493505?pdf=render